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6-Carboxyuracil-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0157S1
    Orotic acid-13C,15N2 monohydrate

    6-Carboxyuracil-<sup>13sup>C,<sup>15sup>N<sub>2sub> monohydrate; Vitamin B13-<sup>13sup>C,<sup>15sup>N<sub>2sub> monohydrate

    		 Nucleoside Antimetabolite/Analog Endogenous Metabolite Metabolic Disease
    Orotic acid- 13C, 15N2 (monohydrate) is the 13C and 15N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4].
    Orotic acid-13C,15N2 monohydrate

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